Coexistence of Raynaud's syndrome and erythromelalgia.

نویسنده

  • G E Slutsker
چکیده

A 40-year-old woman had had, for 5 years, episodes of pallor and blue discoloration of the fingers and toes after cooling and emotional exertion. During these 5 years she also had intolerance to warming of the feet, which manifested attacks of pulsating pain and burning sensations. She had about ten cold and five to seven hot induced paroxysms daily. There were no trophic changes or edema of the fingers and toes. Distal pulsation remained. Adson's and Allen's tests were negative. A cold provocation test induced pallor and blue discoloration of the fingers and toes. A hot provocation test induced pulsating pain and red discoloration of the feet. Biochemical investigation revealed accelerated ADP induced platelet aggregation. The patient was otherwise healthy. She was given nifedipine (40 mg daily), dihydroergocristine (1-5 mg daily), aspirin (750 mg daily), and hyperbaric oxygen sessions (1-7 atmospheres absolute, 45 min, seven sessions). After 3 weeks she was discharged and no longer had either hot or cold induced paroxysms.

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عنوان ژورنال:
  • Lancet

دوره 335 8693  شماره 

صفحات  -

تاریخ انتشار 1990